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SK Bioland,
A Company Creating
a Bountiful Life for Everyone!


Skin Protection

“RHODIOLA EXTRACT”

INCI name : Sedum Rosea Root Extract

Effects : Stress soothing

홍경천

Rhodiola rosea grows high in the mountains of Europe and Asia. This herbaceous perennial flower is also called rock flower in Korea, since it lives on the rocks in the alpine region of the northern midlands of Korea.
The root is eaten raw or cooked, and the Indians in North America used to eat it after fermenting it.
Rhodiola rosea has been used as a traditional medicine for about 3,000 years especially as an adaptogen.
With its adaptogenic effect, it has been widely used in nutraceutical industry for de-stress and reducing depression, and Bioland’s Rhodiola Extract has an excellent effect on soothing skin problems caused by mental stress.

In vitro study

Cytotoxicity (MTT Assay)

  • - PC12(neuroblastoma cell line)
  • - Physio-pathology : Toxicity
홍경천 추출물은 스트레스 유발시 분비되는 neurotransmitter인 susbstance P의 발현을 농도의존적으로 저해함으로써 항스트레스 효능을 보입니다.

Reduction of Neurogenic Inflammation Substance P
Release Assay(pg/ml)

  • - Sensory neurons - Capsaicin stimulation (0.3uM) - ELISA / EIA
  • - Physio-pathology: Peripheral inflammation, Sensitivity,
    Pain, Itching
홍경천 추출물은 스트레스 유발시 분비되는 neurotransmitter인 susbstance P의 발현을 농도의존적으로 저해함으로써 항스트레스 효능을 보입니다.

Histamine Release Assay(nM)

  • - Mast cells (degranulation) ? Compound 48/80 (10ug/ml)
  • - ELISA / ELA
  • - Physio-pathology: Peripheral inflammation, Sensitivity,
    Pain, Itching
홍경천 추출물은 스트레스에 의해 자극된 mast cell에서 과분비된 histamine 의 발현을 감소시킴으로써 항염 효능을 보입니다.

pH stability of Rhodiola Extract

At ph4.5 and higher Clearly dissolved and no precipitation occurred